Table 3.
Percentage of participants who developed aTRH and hazard ratios for incident aTRH associated with baseline albumin to creatinine ratio and eGFR
| No. of cases of incident aTRH/No. who attended visit 2 or 3 | Participants who developed aTRH at visit 2 or 3, % | Age‐ and sex‐adjusted hazard ratio (95% CI) | Multivariable‐adjusteda hazard ratio (95% CI) | |
|---|---|---|---|---|
| ACR, mg/g | ||||
| <10 | 209/1112 | 18.8 | 1 (reference) | 1 (reference) |
| 10–29 | 105/361 | 29.2 | 1.61 (1.21–2.16) | 1.54 (1.15–2.07) |
| ≥30 | 78/268 | 29.1 | 1.66 (1.22–2.26) | 1.44 (1.04–2.00) |
| eGFR, mL/min/1.73 m2 | ||||
| ≥60 | 321/1534 | 20.9 | 1 (reference) | 1 (reference) |
| 45–59 | 50/157 | 31.8 | 1.53 (1.12–2.09) | 1.60 (1.16–2.20) |
| <45 | 21/50 | 42.2 | 2.45 (1.56–3.86) | 2.05 (1.28–3.26) |
Abbreviations: ACR, albumin to creatinine ratio; aTRH, apparent treatment‐resistant hypertension; eGFR, estimated glomerular filtration rate.
a
Adjusted for age, sex, less than high school education, current smoking, physical activity, body mass index ≥30 kg/m2, diabetes mellitus, and history of myocardial infarction.