Table 4.
Incident aTRH associated with study covariates among participants with CKD (n=410)
| Age‐ and sex‐adjusted hazard ratio (95% CI) | Multivariable‐adjustedahazard ratio (95% CI) | |
|---|---|---|
| Age, per 10 y | 1.11 (0.93–1.33) | 1.08 (0.88–1.34) |
| Male sex | 1.55 (1.04–2.30) | 1.67 (1.10–2.52) |
| Less than high school education | 0.96 (0.62–1.49) | 0.90 (0.58–1.40) |
| Current smoking | 0.98 (0.46–2.08) | 1.08 (0.52–2.26) |
| Total physical activity, per exercise unita | 0.95 (0.87–1.04) | 0.98 (0.90–1.07) |
| Body mass index ≥30 kg/m2 | 1.33 (0.87–2.04) | 1.24 (0.81–1.91) |
| Diabetes mellitus | 1.74 (1.20–2.52) | 1.66 (1.12–2.48) |
| History of myocardial infarction | 0.82 (0.43–1.54) | 0.77 (0.40–1.46) |
| ACR, mg/g | ||
| <10 | 1 (reference) | 1 (reference) |
| ≥10 | 1.06 (0.64–1.77) | 1.23 (0.68–2.22) |
| eGFR, mL/min/1.73 m2 | ||
| ≥60 | 1 (reference) | 1 (reference) |
| <60 | 1.44 (0.94–2.19) | 1.70 (1.04–2.79) |
Abbreviations: ACR, albumin to creatinine ratio; aTRH, apparent treatment‐resistant hypertension; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate.
Adjusted for all variables in the left column.
a
Physical activity score ranges from 1 to 20, with a higher score indicating higher physical activity.