Table 2.
Age-, sex-,race/ethnicity-adjusted prevalence (95% CI) and odds ratios (95% CIs) of liver related abnormalities in the U.S. adult population (NHANES 1999–2012) by chronic hepatitis C virus status
| Chronic Hepatitis C | No Chronic Hepatitis C | Odds ratio (95% CI) | |
|---|---|---|---|
| Awareness of Liver Disease | 37.6 (32.2–43.1) | 2.7 (2.5–2.9) | 23.2 (17.8, 30.1) |
| Low albumina, % | 4.3 (2.1–6.6) | 1.2 (1.0–1.3) | 3.9 (2.2–6.8) |
| Low platelets b, % | 12.6 (5.1–20.2) | 1.1 (1.0–1.3) | 13.0 (6.3–26.7) |
| Elevated ALTc, % | 65.1 (58.5–71.7) | 11.6 (11.2–12.1) | 15.2 (11.2–20.6) |
| Elevated ASTc, % | 65.6 (59.7–71.5) | 8.2 (7.9–8.6) | 21.5 (16.5–28.0) |
| Elevated GGTc, % | 58.6 (52.4–64.7) | 13.5 (12.9–14.0) | 9.4 (7.2–12.2) |
| Intermediate APRI (≥0.5), % | 45.9 (40.7–51.1) | 6.4 (6.0–6.7) | 13.0 (10.4–16.2) |
| Elevated APRI (≥1.5), % | 13.7 (8.6–18.8) | 0.3 (0.2–0.4) | 53.1 (32.7–86.4) |
| Elevated FIB-4 (≥1.3), % | 0.9 (0.1–1.8) | 0.1 (0.1–0.2) | 6.3 (1.9–20.9) |
a
Low albumin: <3.5 mg/dL;
b
Low platelets: <100,000 × 103 cells/μL;
c
Elevated ALT: Male: >41 U/L, Female: >31 U/L; Elevated AST: Male: >37 U/L, Female: >31 U/L; Elevated GGT: Male: >49 U/L, Female: >32 U/L.