(a-c; left) Conditioned freezing during extinction training 60 min after receiving a dose of citalopram, reboxetine or RTI-336. (a-c-right) Conditioned freezing the following day (n=8/group). (d) Total average conditioned freezing during extinction training in vehicle- or MDMA-treated mice that received vehicle, citalopram, reboxetine, or RTI-336 60 min prior to extinction training. (n=15 in vehicle pre-treatment groups; n=9 in drug pre-treatment groups) (d) Total average conditioned freezing the day after treatment. *p<0.05; ^p<0.01, #p<0.001.