Table 2.

Summary findings of multiple regression model using the MMSE score as the outcome variable demonstrating a significant regressor effect for the duration of weekly participation in mentally stimulating activities while accounting for confounder variables. Standardized β coefficients are presented. Abbreviations: acetylcholinesterase, AChE; vesicular monoamine transporter type 2, VMAT2.

Duration mentally stimulating activities	Caudate nucleus VMAT2 PET	Cortical AChE PET	Education	Duration	Overall model
β=0.39, t=2.8, p =0.009	β= −0.07, t=−0.5, p=0.6	β=0.35, t=2.4, p=0.024	β= −0.07, t=−0.5, p=0.6	β=0.21, t=1.5, p=0.14	F(6,34)=3.8, P=0.005