Table 2. Anatomical regions where changes in resting state functional connectivity were significantly correlated with changes in self-reported withdrawal symptoms.
Anatomical location | Voxels (mm3) | Max p-value | MNI Coordinates |
---|---|---|---|
Reductions in emotion network rsFC with reductions in craving | |||
L precuneus | 1888 | 0.002 | -26, -58, 12 |
L lateral occipital cortex | 112 | 0.042 | -26, -74, 16 |
L occipital fusiform gyrus | 56 | 0.042 | -26, -78, -8 |
Increases in visuospatial rsFC with reductions in anxiety | |||
L lateral occipital cortex | 240 | 0.032 | -42, -58, 56 |
Increases in right frontoparietal network rsFC with reductions in craving | |||
R frontal pole | 48 | 0.046 | 50, 46, -8 |
Reductions in salience network rsFC with reductions in concentration difficulty | |||
R superior frontal gyrus | 8 | 0.036 | 14, 10, 68 |
Note: L=Left, R=right, rsFC=resting state functional connectivity