Table 1.
Patient demographics in Asian and non-Asian trial populations
| Asiana | Non-Asianb | P value | |||
|---|---|---|---|---|---|
| Celecoxib | Placebo | Celecoxib | Placebo | ||
| n | 145 | 78 | 152 | 66 | |
| Gender, n (%) | 0.1177c | ||||
| Female | 97 (67) | 52 (67) | 88 (58) | 42 (64) | |
| Male | 48 (33) | 26 (33) | 64 (42) | 24 (36) | |
| Age, mean (SD), years | 65.9 (11.1) | 63.9 (11.1) | 58.4 (10.9) | 55.6 (10.4) | <0.0001d |
| Race, n (%) | <0.0001c | ||||
| Asian | 145 (100) | 78 (100) | 0 | 0 | |
| White | 0 | 0 | 93 (61) | 39 (59) | |
| Black | 0 | 0 | 37 (24) | 16 (24) | |
| Other | 0 | 0 | 22 (14) | 11 (17) | |
| Weight, mean (SD), kg | 66.5 (13.3) | 65.6 (12.4) | 87.9 (19.3) | 89.0 (22.2) | <0.0001d |
| Height, mean (SD), cm | 158.6 (8.0) | 158.2 (7.5) | 168.9 (9.7) | 165.8 (10.7) | <0.0001d |
| BMI, mean (SD), kg/m2 | 26.4 (4.8) | 26.1 (4.2) | 30.7 (5.8) | 32.4 (7.5) | <0.0001d |
| Duration of OA, years | |||||
| Mean (SD) | 4.5 (4.0) | 4.6 (4.3) | 6.5 (7.4) | 6.2 (8.1) | 0.0021d |
| Median | 3.0 | 3.2 | 3.1 | 4.0 | |
BMI body mass index, OA osteoarthritis, SD standard deviation
a Patients from study A3191052
b Patients from study A3191063, excluding Asian patients
c Assessed by Chi-square test
d Assessed by t test