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PTHrP induces stem Leydig cell differentiation in vivo. Scheme of PTHrP-treated Leydig cell regeneration for 14 days (A). Serum testosterone levels (B) and LH levels (C). The mRNA levels of Lhcgr, Scarb1, Star, Cyp11a1, Hsd3b1, Cyp17a1, Hsd17b3, Srd5a1, and Hsd11b1 were analyzed by qPCR in the testes treated with 0, 10, and 100 ng/testis PTHrP for 14 days (D). Mean ± SEM, n = 6, *P < 0.05 when compared to the control.
