Fig. 7.

TDF affects mouse NPCs in a dose- and time-dependent manner. Viability of cultured mouse NPCs was determined using the CCK-8. a Mouse NPCs were treated with increasing concentrations of TDF (0.1×, 0.3×, 0.5×, and 1×), and cell viability was measured on day 8. b Mouse NPCs were treated with 0.1× TDF and cell viability was determined on day 2, 4, 6, and 8. Control groups were treated with DMSO. Ara-C (7 μg/ml) served as a positive control. * denotes p < 0.1, ** denotes p < 0.01, **** denotes p < 0.0001 compared with control