Table 5.
Comparison of thyroid measures over time between cases and controls
| Serum parameter | Case | Control | Between groups comparison (P-value)a | ||||
|---|---|---|---|---|---|---|---|
| N | Baseline (mean ± SD | Follow-up (mean ± SD) | N | Baseline (mean ± SD) | Follow-up (mean ± SD) | ||
| FT3 (pmol/L) | 103 | 4.34 ± 0.6 | 4.57 ± 0.2b | 412 | 4.85 ± 0.7 | 4.30 ± 0.5b | <0.001 |
| FT4 (pmol/L) | 103 | 9.06 ± 1.1 | 13.4 ± 1.0b | 412 | 14.7 ± 2.8 | 13.5 ± 1.0b | <0.001 |
| Anti-TPO (kU/L) | 103 | 162.8 ± 120 | 43.4 ± 116b | 412 | 21.5 ± 54.8 | 18.8 ± 26.7 | <0.001 |
| Anti-TG (kU/L) | 103 | 51.8 ± 33.7 | 17.6 ± 27.2b | 412 | 32.0 ± 61.3 | 14.5 ± 30.7b | 0.05 |
| TSH (mlU/L) | 103 | 5.97 ± 4.2 | 2.50 ± 1.1b | 412 | 1.78 ± 0.7 | 1.98 ± 0.6b | <0.001 |
| TG (µg/L) | 31 | 43.1 ± 39.4 | 25.6 ± 4.0b | 244 | 28.2 ± 26.3 | 25.4 ± 5.9 | 0.003 |
| hs-CRP (mg/L) | 103 | 2.05 ± 2.2 | 2.52 ± 1.4 | 412 | 2.35 ± 3.1 | 2.41 ± 1.9 | 0.2 |
| 25(OH)D (nmol/L) | 103 | 68 ± 32 | 110 ± 14b | 412 | 82 ± 34 | 110 ± 27b | 0.001 |
| Vitamin D dose (IU/day) | 103 | 1243 ± 2606 | 3517 ± 2620b | 412 | 1824 ± 2770 | 4150 ± 3321b | 0.9 |
a Independent samples T-test (between groups comparison)
b P < 0.05 paired samples T-test (within group comparison)