Table 2.

Reduced connectivity in depressive patients with suicidal ideation found using the network-based statistics analysis, compared to depressive patients without ideation.

Edges	t -statistics §	Mean functional connectivities		Correlation coefficients with clinical measurements †
		Suicidal Ideation ( n  = 23)	No suicidal ideation ( n  = 23)	Suicidality score	SSI
Left superior frontal gyrus, pars orbitalis* and left caudate	4.51	0.29	0.52	−0.56 ‡	−0.24
Left superior frontal gyrus, pars orbitalis* and right caudate	4.33	0.27	0.48	−0.47 ‡	−0.24
Left superior frontal gyrus, pars orbitalis* and right olfactory cortex	4.38	0.19	0.40	−0.47 ‡	−0.34 ‡
Left superior frontal gyrus, pars orbitalis* and right putamen	4.60	0.11	0.33	−0.54 ‡	−0.40 ‡
Left thalamus* and left superior frontal gyrus, pars orbitalis*	4.89	0.10	0.32	−0.57 ‡	−0.42 ‡
Left thalamus* and left middle frontal gyrus, pars orbitalis	4.36	0.13	0.35	−0.50 ‡	−0.41 ‡
Left thalamus* and left middle temporal gyrus	4.47	0.34	0.54	−0.48 ‡	−0.40 ‡
Right thalamus* and left superior frontal gyrus, pars orbitalis*	5.19	0.061	0.29	−0.58 ‡	−0.40 ‡
Right thalamus* and left middle frontal gyrus, pars orbitalis	4.21	0.084	0.32	−0.56 ‡	−0.37 ‡
Right thalamus* and left middle temporal gyrus	5.40	0.24	0.51	−0.54 ‡	−0.35 ‡
Right thalamus* and left postcentral gyrus	4.64	0.20	0.49	−0.56 ‡	−0.52 ‡

SSI, Scale for Suicide Ideation.

^§t-statistic from 2-sample t-test, (MDD_without − MDD_with).

^*hub nodes.

^†Spearman partial correlation coefficients between functional connectivities and Suicidality score/SSI scores in total MDD patients.

^‡BOLD: significant after FDR correction over 11 edges (FDR-adjusted p-value < 0.05).