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Diversity of residues encoded by transcripts of different germline gene origins in position 29 of VH of IgG. The germline-encoded residues and their frequencies in IgG-encoding transcripts are shown at the bottom of the graph. Note the extensive diversification of S29 in IgG-encoding transcripts derived from IGHV5-51 but not from other genes, in particular IGHV2-5, IGHV4-39, and IGHV4-59.
