Table 3.

Cerebrospinal fluid cytokine levels before and 24 h after surgery (n = 40).

Biomarker	Mean pg/ml (SE) at 0 h	Mean pg/ml (SE) at 24 h	Raw p value	Bonferroni corrected p value
EGF	5.80 (0.73)	6.98 (0.96)	0.3387	>0.99
Eotaxin	9.70 (3.18)	12.17 (3.59)	0.1344	>0.99
G-CSF	20.77 (6.62)	2,170.23 (455.64)	<0.00005	<0.001
GM-CSF	2.75 (0.43)	7.72 (2.95)	0.0942	>0.99
IFN-α2	12.65 (0.81)	16.03 (1.49)	0.2732	>0.99
IL-10	1.57 (0)	133.31 (45.74)	<0.00005	<0.001
IL-1RA	11.79 (7.26)	342.97 (181.44)	0.0001	0.002
IL-6	1.81 (0.16)	11,543.85 (3149.69)	<0.00005	<0.001
IL-7	1.56 (0.04)	2.47 (0.32)	0.0036	0.054
IL-8	97.35 (22.72)	22,388.83 (6926.77)	<0.00005	<0.001
IP-10	645.57 (112.33)	7,984.34 (1,718.99)	<0.00005	<0.001
MCP-1	766.13 (120.82)	35,689.67 (7,469.17)	<0.00005	<0.001
MIP-1α	1.61 (0)	6.92 (1.33)	<0.00005	<0.001
MIP-1β	2.76 (0.6)	117.68 (40.85)	<0.00005	<0.001
TNF-α	1.60 (0)	4.92 (0.78)	<0.00005	<0.001