Table 4.
Risk and predictive performance analysis of simple risk system for diabetic cardiovascular autonomic neuropathy in total sample an external dataset.
| Cutoff point | Total sample | External dataset | ||
|---|---|---|---|---|
| 7 (Score 0–7) | 18 (Score 18–25) | 7 (Score 0–7) | 18 (Score 18–25) | |
| Risk value | Low risk | High risk | Low risk | High risk |
| Sensitivity (%) | 97.22 (91.12–103.33) | 25.22 (24.99–25.45) | 96.15 (95.18–97.13) | 23.08 (22.97–23.18) |
| Specificity (%) | 24.82 (14.41–35.23) | 98.88 (88.21–109.55) | 31.4 (20.43–42.37) | 97.5 (87.23–107.77) |
| Youden Index (%) | 22.04 (13.48–30.6) | 24.1 (15.9–32.3) | 27.55 (18.83–36.28) | 20.58 (11.74–29.42) |
| PPV (%) | 34.22 (27.3–41.15) | 90.05 (83.47–96.63) | 47.67 (41.38–53.95) | 85.71 (79.34–92.09) |
| NPV (%) | 95.69 (92.19–99.19) | 76.67 (73.53–79.82) | 92.63 (89.07–96.19) | 66.11 (63.07–69.14) |
| % Total sample | 18.65 (13.72–23.59) | 8.81 (4.53–13.09) | 24.24 (19.68–28.8) | 10.61 (6.6–14.62) |
PPV – positive predictive value; NPV – negative predictive value; The confidence intervals (CIs) for sensitivity, specificity, and predictive values were calculated using bootstrapping (1000).