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. 2017 Nov 14;12:8257–8275. doi: 10.2147/IJN.S143776

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© 2017 Shi et al. This work is published and licensed by Dove Medical Press Limited

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In vitro antitumor efficacy of PNLs.

Notes: (A) Detection of intracellular ROS by DCFH-DA staining in MCF-7/MDR cells; scale bar represents 20 μm. (B) Cytotoxicity of the BNL (n=6). (C) Cell viability of different treatments on MCF-7/MDR cells incubation for 24 h (n=6). (D) Apoptosis in MCF-7/MDR cells of different treatments. Data presented are mean ± SD. ***P<0.01, PNLs vs PNLs+laser.

Abbreviations: DOX, doxorubicin; HMME, hematoporphyrin monomethyl ether; MDR, multidrug resistance; NL(DOX), DOX-loaded nanoliposome; NL(HMME), HMME-loaded nanoliposome; PNLs, photo-activated nanoliposomes; ROS, reactive oxygen species.