Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Kinetic parameters obtained for binding of FcγRIIIA with the IgG3 Fc glycovariants
| IgG3 Fc glycoform |
Average kon*105 (1/M.sec) |
Average koff*10−3 (1/sec) |
Average KD (nM) |
|---|---|---|---|
| Man8-Man12 | 1.6 ± 0.1 | 6.5 ± 0.2 | 41.4 ± 2.7 |
| Man5 | 1.5 ± 0.1 | 6.8 ± 0.2 | 46.5 ± 2.4 |
| Fc-GlcNAc | 1.7 ± 0.4 | 85.8 ± 7.7 | 506 ± 113 |
| D297 | nd* | nd* | nd* |
not detected at highest receptor concentration of 15 μ
