Conceptual model for complex mediation analysis of the association between county urbanicity and cancer incidence rates, without and with adjustment for four simultaneous mediators: socioeconomic status (SES) quintile, percent non-Hispanic white population, physician density per 1,000 residents, and cancer screening rate. Subscripts of pathway estimates reflect coefficients of the association between dependent and independent variables, and control variables, if applicable (e.g., β̂IU·SWPR is the coefficient for cancer incidence regressed on urbanicity, adjusted for SES quintile, non-Hispanic white density, physician density, and screening rate).