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. 2017 Nov 14;8:600. doi: 10.3389/fneur.2017.00600

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Copyright © 2017 Guinand, Van de Berg, Cavuscens, Ranieri, Schneider, Lucieer, Kingma, Guyot and Pérez Fornos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Median (±25th–75th percentiles) angular vestibulo-ocular reflex (aVOR) gains (vertical axis) for the three patients as a function of stimulation condition (horizontal axis): (A) S1 right anterior–left posterior (RALP), (B) S2 horizontal, and (C) S3 RALP. Note that a transfer function with a slope of 0 µA/°/s corresponds to constant amplitude electrical stimulation that is not modulated by motion (i.e., baseline stimulation only). Results for excitatory head impulses are plotted in red and results for inhibitory head impulses are plotted in blue. Results without electrical stimulation (system OFF) are presented as the colored solid bars in the graph. The green dotted line represents the theoretical aVOR gain of 1 for a normal subject with a “healthy” vestibular system.