Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 14;8:819. doi: 10.3389/fphar.2017.00819

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Chiang, Liang, Liu, Pan, Chen, Yang, Lee, Tsai, Lee and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Aliskiren adminstration strongly decreases apoptosis and increases autophagy in MI mice. (A) TUNEL staining of the infarct zone of the control, MI and MI + ALI group at the indicated time (Blue: nuclei; green: apoptotic cell). Bar = 50 μm. (B) Apoptotic index as the percentage of TUNEL-positive nuclei compared with total nuclei. (C,D) The representative immunoblot and statistical analysis showed caspase-3 (C), Bcl-2, and LC3B II (D) expression in cardiac samples. GAPDH was used as an internal control. (E) LC3B expression in cardiac tissues was stained by immunohistochemistry. Bar: 100 μm. Each of the experiments was repeated three times. The data are means ± SEM. ^∗P < 0.05 compared with the control group. ^†P < 0.05 compared with the MI group at the indicated times.