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AdipoRon, a small AdipoR agonist, doesn't exert anti-inflammatory effects on BV2 cells. BV2 cells were pre-treated with vehicle or AdipoRon (10−6 M) before treatment with LPS (0.5 μg/ml) for the indicated period of time. Levels of IL-1β, IL-6, TNFα mRNAs were quantified by qRT-PCR. N = 5–7, two-way analysis of variance (ANOVA) was carried out, ns, non-significant.
