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Physiological response of C. albicans to metal starvation. C. albicans (BWP17 + Clp30) cells subjected to copper (A), iron (B), manganese (C), and zinc (D) starvation by incubating in limiting medium independently lacking these metals at 30°C, 200 rpm for 3 days. Experiment performed twice. DIC images show that of the metals tested only zinc starvation resulted in cellular enlargement in C. albicans. Scale bar represents 5 μm.
