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. 2017 Nov 14;8:2238. doi: 10.3389/fmicb.2017.02238

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Copyright © 2017 Malavia, Lehtovirta-Morley, Alamir, Weiß, Gow, Hube and Wilson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular gigantism in multiple C. albicans clinical isolates. Indicated C. albicans clinical isolates pre-grown in SD medium were incubated in LZM for 3 days at 30°C, 200 rpm. DIC images show that all the tested clinical isolates can enlarge to varying degrees upon zinc depletion. Clinical isolates belonging to Clade 1 enlarged to a greater degree than other isolates. All the strains are distinctly bigger than the LZM + Z control. Scale bar represents 5 μm.