Table 4.

Logistic regression analysis and AUC for models of CAD adjusted for age and sex.

Variable	24-h			Awake			Sleep
	ORn [95% CI]	AUC	p	ORn [95% CI]	AUC	p	ORn [95% CI]	AUC	p
PIPH	3.24 [2.04–5.16]	0.911	1.55E-08	3.30 [2.03–5.35]	0.910	4.11E-08	2.03 [1.41–2.93]	0.897	4.38E-05
PIPS	0.78 [0.57–1.07]	0.885	1.23E-01	0.73 [0.53–1.01]	0.885	5.20E-02	0.96 [0.69–1.33]	0.882	8.01E-01
W0	0.37 [0.24–0.55]	0.907	1.80E-07	0.41 [0.28–0.62]	0.902	3.94E-06	0.56 [0.40–0.79]	0.894	5.48E-04
W1	0.39 [0.26–0.59]	0.900	2.56E-06	0.52 [0.35–0.77]	0.893	6.60E-04	0.42 [0.29–0.62]	0.898	2.17E-06
${\text{W}}_1^{\text{H}}$	0.56 [0.39–0.82]	0.890	1.91E-03	0.77 [0.55–1.08]	0.882	1.26E-01	0.46 [0.32–0.68]	0.894	2.44E-05
${\text{W}}_1^{\text{H}*}$	0.31 [0.20–0.48]	0.910	5.97E-09	0.37 [0.24–0.57]	0.905	8.62E-07	0.42 [0.29–0.60]	0.902	4.94E-07
${\text{W}}_1^{\text{S}}$	0.48 [0.34–0.66]	0.901	3.70E-06	0.47 [0.34–0.66]	0.901	5.33E-06	0.67 [0.49–0.91]	0.889	8.87E-03
${\text{W}}_1^{\text{S}*}$	0.26 [0.16–0.43]	0.910	5.26E-09	0.35 [0.22–0.56]	0.902	2.14E-06	0.58 [0.40–0.82]	0.890	1.76E-03
W2	2.79 [1.86–4.19]	0.906	3.34E-08	2.36 [1.58–3.53]	0.899	5.12E-06	2.05 [1.46–2.89]	0.896	9.13E-06
${\text{W}}_2^{\text{H}}$	2.33 [1.60–3.38]	0.904	1.43E-06	2.36 [1.59–3.50]	0.902	3.37E-06	1.78 [1.29–2.46]	0.894	2.55E-04
${\text{W}}_2^{\text{H}*}$	2.86 [1.95–4.21]	0.910	4.46E-09	2.78 [1.83–4.24]	0.907	4.41E-07	2.19 [1.56–3.06]	0.899	1.03E-06
${\text{W}}_2^{\text{S}}$	0.53 [0.38–0.73]	0.897	7.78E-05	0.52 [0.37–0.73]	0.897	6.33E-05	0.68 [0.50–0.93]	0.888	1.51E-02
${\text{W}}_2^{\text{S}*}$	1.62 [1.17–2.26]	0.889	3.17E-03	1.63 [1.16–2.29]	0.890	3.35E-03	1.08 [0.78–1.49]	0.882	6.35E-01
${\text{W}}_2^{\text{M}}$	0.92 [0.66–1.28]	0.882	6.19E-01	0.90 [0.64–1.26]	0.882	5.25E-01	0.96 [0.70–1.33]	0.882	8.09E-01
W3	1.75 [1.15–2.67]	0.889	6.03E-03	1.53 [1.04–2.24]	0.886	2.61E-02	1.78 [1.15–2.74]	0.888	5.71E-03
${\text{W}}_3^{\text{H}}$	2.69 [1.42–5.09]	0.895	2.99E-04	2.52 [1.38–4.61]	0.895	4.19E-04	1.96 [1.09–3.53]	0.887	9.21E-03
${\text{W}}_3^{\text{H}*}$	1.77 [1.10-2.86]	0.888	8.96E-03	1.48 [0.99–2.20]	0.885	4.17E-02	1.74 [1.05–2.90]	0.886	1.80E-02
${\text{W}}_3^{\text{S}}$	0.73 [0.54–1.01]	0.886	5.52E-02	0.69 [0.50–0.94]	0.887	1.69E-02	0.93 [0.67–1.31]	0.882	6.88E-01
${\text{W}}_3^{\text{S}*}$	1.30 [0.90–1.88]	0.882	1.54E-01	1.16 [0.81–1.66]	0.883	4.11E-01	1.54 [1.05–2.26]	0.886	2.03E-02
${\text{W}}_3^{\text{M}}$	1.51 [1.02–2.25]	0.886	3.23E-02	1.37 [0.95–1.98]	0.884	8.71E-02	1.63 [1.09–2.44]	0.887	1.26E-02

The analysis was performed using raw measures. Values presented are the normalized odds ratio (OR_n) and the 95% confidence intervals (95% CI) for the variables listed in the header column, in models adjusted for age and sex; the area under the receiver operating characteristic curve (AUC) and the p value for the likelihood-ratio test of the null hypothesis that the addition of the HRV measure does not improve the fit of the model with age and sex alone. CAD, coronary artery disease; PIP, percentage of inflection points; W_j, 0 ≤ j ≤ 3, group of words containing j inflection points; superscripts: H, hard inflection points; S, soft inflection points; M, mixed inflection points, i.e., a combination of hard and soft inflection points. Word groups for which the type of inflection point is not specified comprise words with all types of inflection points. The percentages of words in the groups $W_j^{H*}$ and $W_j^{S*}$ were calculated over the total number of NN words with only hard and only soft inflection points, respectively. The percentages of words in the other groups were calculated over the total number of NN words.