Table 2.
Pathway analysis of the three identified metabolites (taurine, gamma-aminobutyric acid, and uracil) using MetaboAnalyst. These metabolites were related to nine metabolic pathways.
| No. | Metabolic pathway | Total | Expected | Hits | FDR | Impact |
|---|---|---|---|---|---|---|
| 1 | Beta-alanine metabolism | 28 | 0.034898 | 2 | 0.031104 | 0 |
| 2 | Taurine and hypotaurine metabolism | 20 | 0.024927 | 1 | 0.65401 | 0.33094 |
| 3 | Alanine, aspartate, and glutamate metabolism | 24 | 0.029913 | 1 | 0.65401 | 0.10256 |
| 4 | Pantothenate and CoA biosynthesis | 27 | 0.033652 | 1 | 0.65401 | 0 |
| 5 | Nitrogen metabolism | 39 | 0.048608 | 1 | 0.65401 | 0 |
| 6 | Butanoate metabolism | 40 | 0.049855 | 1 | 0.65401 | 0.01067 |
| 7 | Primary bile acid biosynthesis | 47 | 0.058579 | 1 | 0.65676 | 0.00822 |
| 8 | Pyrimidine metabolism | 60 | 0.074782 | 1 | 0.72963 | 0.07132 |
| 9 | Arginine and proline metabolism | 77 | 0.09597 | 1 | 0.8264 | 0.01905 |