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. Author manuscript; available in PMC: 2017 Nov 19.
Published in final edited form as: Immunity. 2016 Nov 1;45(5):975–987. doi: 10.1016/j.immuni.2016.10.011

Figure 7. E2 is a monocyte-specific enhancer.

Figure 7

a) Gating scheme for tissue macrophage sorting. All cells were previously gated on live singlets. The side scatter high profile of lung CD11c+ macrophages is shown in the right panel (blue). b and c) Relative Nr4a1 mRNA expression in tissue macrophages and blood Ly6Chi and Ly6Clow Mo. Statistics for b) and c) measured by students t-test * p<0.05, ** p<0.01. d) Representative sections of B16F10 tumors in WT, Nr4a1−/− and E2 domain-deficient mice. e) and f) Quantification of cancer metastasis area, error bars represent SD statistics were analyzed by ANOVA * p<0.05. Please refer to supplementary figure S7.