Table 4.

Hazard Ratios and 95% CIs for the Association Between Sitting Time, Total Physical Activity, and Risk of Colorectal Cancer, Stratified by Age Group, BMI Group and Employment

	Sitting Time (hrs/day)				Physical Activity (MET-hrs/week)
	≤ 5	5.1–9.9	≥ 10	p trend	Inactive (≤1.7)	Low (1.8–7.4)	Medium (7.5–20)	High (>20)	p trend
Colorectal
Age Group1
50–59	1.00	1.17 (0.82–1.65)	1.26 (0.84–1.87)	0.45	1.00	1.13 (0.75–1.69)	0.87 (0.58–1.32)	0.83 (0.52–1.33)	0.19
60–69	1.00	1.09 (0.89–1.33)	1.06 (0.80–1.41)	0.82	1.00	0.86 (0.65–1.14)	0.92 (0.71–1.19)	0.78 (0.58–1.06)	0.17
70+	1.00	1.14 (0.90–1.46)	1.21 (0.85–1.72)	0.26	1.00	0.99 (0.72–1.38)	0.98 (0.72–1.35)	0.90 (0.63–1.29)	0.49
BMI Group2
Normal	1.00	1.03 (0.82–1.28)	0.86 (0.61–1.21)	0.43	1.00	0.97 (0.61–1.39)	0.85 (0.61–1.20)	0.72 (0.50–1.04)	0.02
Overweight	1.00	1.22 (0.95–1.56)	1.34 (0.96–1.87)	0.09	1.00	0.86 (0.62–1.20)	0.96 (0.70–1.31)	0.93 (0.65–1.32)	0.09
Obese	1.00	1.12 (0.84–1.50)	1.22 (0.86–1.73)	0.30	1.00	1.08 (0.79–1.47)	1.07 (0.79–1.46)	1.00 (0.67–1.50)	0.67
Employment3
Employed	1.00	1.17 (0.87–1.56)	1.16 (0.93–1.62)	0.48	1.00	0.92 (0.66–1.28)	0.86 (0.62–1.19)	0.68 (0.46–0.99)	0.04
Unemployed	1.00	1.11 (0.95–1.31)	1.14 (0.89–1.45)	0.25	1.00	0.95 (0.75–1.20)	0.96 (0.77–1.20)	0.89 (0.69–1.14)	0.26

MV model: Race, education, total caloric intake, fiber intake, calcium intake, vitamin D intake, red meat intake, alcohol, hormone replacement therapy, income, marital status, smoking, family history of CRC, CRC screening, aspirin, multivitamin use, physical activity (ST model), and sitting time (PA model)

¹Age Group: P for interaction: ST = 0.97 & PA = 0.55

²BMI Group: P for interaction: ST = 0.66 & PA = 0.80

³Employment: P for interaction: ST = 0.99 & PA = 0.96