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. 2017 Nov 15;8:317. doi: 10.3389/fendo.2017.00317

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Copyright © 2017 Wang, Chen, Liu, Guo, Du, Yuan, Guo, Kang, Sun and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Wnt4 and follicle-stimulating hormone (FSH) on mRNA expression of steroidogenic enzyme genes and steroidogenesis in prehierarchical and hierarchical follicles. (A) Effects of Wnt4 and FSH on StAR, CYP11A1, and follicle-stimulating hormone receptor (FSHR) mRNA expression and progesterone secretion in the granulosa cells (GCs) of prehierarchical follicles. Bars with different superscript letters are significantly different. (B) Effects of Wnt4 and FSH on StAR, CYP11A1, and FSHR mRNA expression and progesterone secretion in the GCs of hierarchical follicles. (^ABCp < 0.01).