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. 2017 Nov 15;8:317. doi: 10.3389/fendo.2017.00317

Table 3.

Significantly enriched pathways.

Pathway p Value UniGene number
T1 vs. T4

Focal adhesion 0 76
ECM–receptor interaction 6.80E−13 46
Cytokine–cytokine receptor interaction 1.42E−09 52
Cell adhesion molecules 1.13E−07 33
TGF-β signaling pathway 0.000100699 21
Vascular smooth muscle contraction 0.000111614 27
Amebiasis 0.000368349 6
Melanogenesis 0.000937358 22
Calcium signaling pathway 0.003524408 33
Adherens junction 0.004793109 17
MAPK signaling pathway 0.005027368 43
Regulation of actin cytoskeleton 0.006272819 36
Wnt signaling pathway 0.006320051 27
Gap junction 0.0071262 18
Steroid hormone biosynthesis 0.009703041 9
Arrhythmogenic right ventricular cardiomyopathy 0.013001616 5
VEGF signaling pathway 0.01314305 15
Gastric acid secretion 0.013974998 2
Intestinal immune network for IgA production 0.024274613 8
Phosphatidylinositol signaling system 0.028484703 16

T2 vs. T5

PPAR signaling pathway 0.007689374 4
Focal adhesion 0.016837656 7
Progesterone-mediated oocyte maturation 0.019698938 4
Dorsoventral axis formation 0.03060988 2
Cardiac muscle contraction 0.035262584 3
Lipoic acid metabolism 0.039079049 1
Oocyte meiosis 0.040688919 4
Adipocytokine signaling pathway 0.047671798 3
Wnt signaling pathway 0.848944256 1

T3 vs. T6

Steroid biosynthesis 0.0003184 5
Phagosome 0.0042824 12
NOD-like receptor signaling pathway 0.005853671 6
Terpenoid backbone biosynthesis 0.017505751 3
DNA replication 0.031551297 4
Glycosaminoglycan biosynthesis—chondroitin sulfate 0.048837386 3
Wnt signaling pathway 0.441815127 6