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. 2017 Nov 15;8:928. doi: 10.3389/fphys.2017.00928

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Copyright © 2017 Hao, Liu, Pan, Wang, Gao, Fan and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Rhy restores endothelial function concentration-dependently in SHR renal arteries. (A) Endothelium-dependent relaxation in response to ACh in the arteries from SHRs incubated with Rhy (30, 100, or 300 μM) or vehicle for 12 h. (B) Endothelium-independent relaxation response to SNP in SHR renal arteries. (C) Effects of Rhy on eNOS phosphorylation in the renal arteries from SHRs. (D) Effects of Rhy on NO production in the renal arteries from SHRs. n = 6; ^*p < 0.05 vs. vehicle.