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Expression of pTAU (using the AT8 antibody) in the frontal cortex (A,B) and the hippocampus (C,D) of male (A,C) and female (B,D), young (3 months, 3 m) and aged (18 months, 18 m), control wild type (WT) and adm knockout (KO) mice. Two-way ANOVA: *p < 0.05 interaction, &p < 0.05, &&p < 0.01 main effect of age. Panels show percentage of optical density (OD) values of control and representative pictures of the blotting. β-Actin is used as internal loading control.
