Table 5.

Comparison of variants identified by SMRT Sequencing and Sanger sequencing in pre-treatment and post-treatment strain.

Genes	Pre-treatment strain		Post-treatment strain
	SMRT Sequencing	Sanger sequencing	SMRT Sequencing	Sanger sequencing
rpoB	S531L (tCg → tTg)	S531L (tCg → tTg)	S531L (tCg → tTg)	S531L (tCg → tTg)
katG	WT	WT	WT	WT
inhA	C-15T	C-15T	C-15T	C-15T
embB	M306V (Atg → Gtg)	M306V (Atg → Gtg)	M306V (Atg → Gtg)	M306V (Atg → Gtg)
ubiA	WT	WT	WT	WT
pncA	G162D (gGt → gAt)	G162D (gGt → gAt)	G162D (gGt → gAt)	G162D (gGt → gAt)
rpsL	R43K (aAg → aGg)	R43K (aAg → aGg)	R43K (aAg → aGg)	R43K (aAg → aGg)
gyrA	WT	WT	WT	WT
gyrB	WT	WT	WT	WT
rrs	A1401G	A1401G	A1401G	A1401G
tlyA	WT	WT	WT	WT
ethA	WT	WT	WT	WT
folC	WT	WT	WT	WT
rv0888	360delG	360delG	WT	WT
rv2071c	WT	WT	199_204delGCCGAC	199_204delGCCGAC
rv2921c	WT	WT	1244_1251delATTCGTCG	WT
rv3303c	WT	WT	V44I (Gta → Ata)	V44I (Gta → Ata)