Phylogeography of Lassa virus and its reservoir host M. natalensis.
(A) Phylogeny of Lassa virus isolates from humans and rodents, and (B) reconstructed LASV evolutionary history across West Africa. (C) Cytochrome b phylogenetic tree of M. natalensis sampled from across the species’ full range of sub-Saharan Africa, and (D) the geographical distribution of samples. M. natalensis in West Africa form a separate clade from the rest of the continent (clade 1, shown in green). LASV appears to only occur in this western clade. (A–B reproduced from [70], with permission from Elsevier. C–D reproduced from [38], © 2016 The Authors, under CC BY 4.0 license https://creativecommons.org/licenses/by/4.0/).