Table 2. Gene expression of hearts with AVO at one and three days compared with controls.
Controls | AVO day 1 | Mann-Whitney U-test p-value | AVO day 3 | Mann-Whitney U-test p-value | Kruskall-Wallis test p-value | |
ANP | 1.00 ± 0.22 | 2.64 ± 0.57 | 0.019 | 2.08 ± 0.66 | 0.165 | 0.055 |
MMP9 | 1.00 ± 0.39 | 9.64 ± 2.33 | 0.003 | 5.84 ± 1.37 | 0.006 | 0.005 |
TGFβ | 1.00 ± 0.12 | 4.06 ± 0.80 | 0.002 | 2.96 ± 0.33 | 0.004 | 0.003 |
YKL40 | 1.00 ± 0.26 | 10.79 ± 1.70 | 0.001 | 3.91 ± 0.60 | 0.003 | 0.001 |
Values are expressed as mean ± standard error of mean.
ANP, atrial natriuretic peptide; AVO, acute volume-overload; MMP9, matrix metalloproteinase 9; TGFβ, tumor growth factor β; YKL40, chitinase 3-like protein.