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. 2017 Oct 2;149(10):951–966. doi: 10.1085/jgp.201711769

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© 2017 Pulupa et al.

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Figure 7. — Filaments translocate the nuclear envelope. (A) Translocation event of a single FG-Nup49 filament under the no FG-bonding condition; all axes are in nanometers. (B) For all binding conditions, the fraction that translocate is defined as the fraction of filaments that started the simulation on the cytoplasmic side of the NPC and eventually made it into the nucleus. (C) Time to translocate is defined as the time elapsed between entering the NPC on one side and emergence on the opposite side, in either direction. (D) Time to translocate for filaments composed of segments of different sizes. All plots are mean ± SD.