Table 1.1.

Characteristics of CSF-1- and IL-34-derived X. laevis peritoneal macrophages

	Effector molecules expressed	Increased effector functions	Proposed function	References
CSF-1-derived	iNOSa	Phagocytosis, NO production Microbicidal activity	Antibacterial	Grayfer and Robert (2014, 2015)
IL-34-derived	Arginase-l NADPH oxidase Type I IFNb	ROS production Antiviral activity	Antiviral	Grayfer and Robert (2014, 2015)

^aSignificantly higher iNOS expression in CSF-1-derived than IL-34-derived adult peritoneal macrophages

^bSignificantly higher Type I IFN gene expression response in tadpole but not adult IL-34- derived peritoneal macrophages compared to respective CSP-derived peritoneal macrophages