Table 3.

Mean levels of periodontal microorganism (standard errors) and relative (fold) changes for rs6940 and rs1057028 haplotype blocks (adjusted for plaque levels).

SNP	N	Pg	Pi	Pn	Tf	Td	Cr	Fn	Aa
rs6940*
1.1	781	2.22 (0.06)	2.55 (0.07)	2.68 (0.07)	2.43 (0.06)	2.61 (0.07)	2.66 (0.07)	2.86 (0.08)	2.57 (0.06)
1.2	255	2.27 (0.10)	2.71 (0.13)	2.51 (0.13)	2.49 (0.11)	2.53 (0.12)	2.72 (0.11)	2.96 (0.13)	2.74 (0.10)
2.2	17	3.54 (0.43) ‡	3.01 (0.54)	3.47 (0.52)	3.50 (0.45)†	3.11 (0.48)	3.69 (0.48)†	3.94 (0.55)	2.99 (0.44)
Fold change	274.34	58.41	120.34	191.54	64.87	180.11	194.47	52.20
rs1057028*
1.1	711	2.24 (0.06)	2.62 (0.08)	2.71 (0.08)	2.42 (0.07)	2.63 (0.07)	2.67 (0.07)	2.86 (0.08)	2.59 (0.06)
1.2	300	2.21 (0.10)	2.48 (0.12)	2.42 (0.12)	2.46 (0.10)	2.47 (0.11)	2.65 (0.11)	2.90 (0.12)	2.58 (0.10)
2.2	42	2.89 (0.26)†	3.07 (0.32)	3.31 (0.31)	3.13 (0.27)†	2.92 (0.29)	3.34 (0.29)†	3.55 (0.33)†	3.25 (0.26)†
Fold change	91.55	56.83	82.21	103.40	33.64	95.42	99.37	93.48

^*haplotype blocks for both SNPs include additional SNPs shown on Table 1.

Genotypes, 1.1: homozygous for the major allele, 1.2: heterozygous, 2.2: homozygous for the minor allele.

Chi-square p-values using 1.1 as the referent category:

^†p≤0.05,

^‡p≤0.01; fold change comparing 2.2 vs. 1.1