CATH-2 silently kills P. aeruginosa. Various concentrations of P. aeruginosa cells were left untreated or were CATH-2 killed, heat killed, or gentamicin killed and used for colony counting assays (A) or stimulation of J774.A1 cells for 2 h (B), after which TNF-α release was determined. Statistical differences were determined by two-way ANOVA with Bonferroni's post hoc test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. n = 3. Error bars = SEM.