Table 2.
Stability of [44Sc]Sc-PSMA-617 at 37 °C in the presence of different metal cations and in the presence of DTPA and EDTA, at 10-2 M concentration respectively (n = 3).
Time (h) | % intact [44Sc]Sc-PSMA-617±SD | ||||
---|---|---|---|---|---|
Ca2+ | Mg2+ | Fe3+ | EDTA | DTPA | |
0.5 | 98.0±0.0 | 98.7±0.5 | 97.3±0.9 | 96.7±0.1 | 96.7±1.2 |
1 | 98.3±0.5 | 98.3±0.5 | 98.0±0.8 | 97.3±0.1 | 97.7±0.5 |
2 | 97.0±0.1 | 98.0±0.8 | 98.0±0.8 | 97.3±0.1 | 97.0±0.8 |
4 | 97.0±1.4 | 97.7±0.5 | 96.7±0.5 | 97.3±0.1 | 96.7±0.5 |
24 | 96.7±0.8 | 97.2±0.8 | 95.0±1.4 | 95.9±1.2 | 95.1±0.8 |