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Statistical analysis of pulmonary transit time extracted from the time-resolved volumetric optoacoustic data. (a) PTT of infarcted hearts (2.25 [2.00-2.41] s) were significantly higher than that of healthy mice (1.34 [1.25-1.67] s, p = 0.0235). (b) PTT at different time points after infarction surgery: 3 days (2.79 [2.69-2.87] s), 10 days (2.35 [2.07-2.40] s), and 21 days (2.05 [1.90-2.18] s), (p < 0.0001).
