Table 1.
RT-qPCR analysis of selected candidate target genes of HOXA5 in the medulla oblongata and pons.
| Target genes | Fold change | p-value | |
|---|---|---|---|
| Medulla | Cadps2 | 1.52 | 0.0052∗∗ |
| Oblongata | Wnt7a | 3.21 | 0.0076∗∗ |
| Zic2 | 1.61 | 0.0061∗∗ | |
| NeuroD2 | 1.45 | 0.0063∗∗ | |
| Zic1 | 1.37 | 0.0088∗∗ | |
| Prkcg | 1.30 | 0.0091∗∗ | |
| Grm4 | 1.56 | 0.0243∗ | |
| Adcy1 | 1.60 | 0.0381∗ | |
| Homer3 | 1.26 | 0.0463∗ | |
| Gabra6 | 2.49 | 0.0672 | |
| En2 | 1.42 | 0.2089 | |
| Slc1a6 | 1.49 | 0.2856 | |
| Cbln3 | 1.27 | 0.2662 | |
| Calb1 | 0.95 | 0.6538 | |
| Pons | Calb1 | 1.30 | 0.0519 |
| Zic1 | 1.22 | 0.1649 |
p-values are from ANOVA test. n = 3–6 for Hoxa5 control brains, n = 3–8 for Hoxa5 cKO brains. Asterisks depict statistically significant differences in Hoxa5 cKO brains compared with Hoxa5 control brains: ∗∗p < 0.01 and ∗p < 0.05.