Table 2.
Neuroanatomical localization of HOXA5 candidate target genes expression in Hoxa5-expressing nuclei, as evaluated by in situ hybridization analysis.
| HOXA5 positive nuclei | Detected transcripts | |
|---|---|---|
| Medulla | XII (hypoglossal nucleus) | Calb1, Itpr1, Vglut1, Wnt7a |
| Oblongata | X (nucleus x) | Cbln1, Grin2c, Vglut1, Zic1 |
| SPIV (spinal vestibular nucleus) | Cadps2 | |
| MV (medial vestibular nucleus) | Cadps2, Grin2c, Zic1 | |
| PRP (nucleus prepositus) | Cadps2, Grin2c, Zic1 | |
| PARN (parvicellular reticular nucleus) | Calb1, Cbln1 | |
| MDRN (medullary reticular nucleus) | Calb1 | |
| IRN (intermediate reticular nucleus) | Itpr1 | |
| GRN (gigantocellular reticular nucleus) | Cadps2, Cbln1 | |
| DMX (dorsal motor nucleus of the vagus nerve) | Cadps2, Calb1 | |
| LRN (lateral reticular nucleus) | Camk4, Cbln1, NeuroD2, Vglut1, Zic1, Zic2 | |
| SPVI (spinal nucleus of the trigeminal, interpolar part) | Cbln1, Itpr1, Vglut1 | |
| SPVC (spinal nucleus of the trigeminal, caudal part) | Adcy1, Calb1, Cbln1 | |
| NTS (nucleus of the solitary tract) | Calb1, Cbln1, Zic1 | |
| ECU (external cuneate nucleus) | Camk4, Cbln1, Grin2c, Vglut1, Zic1, Zic2 | |
| GR (gracile nucleus) | Cbln1 | |
| CU (cuneate nucleus) | Cbln1 | |
| AP (area postrema) | Zic1 | |
| Pons | IF5 (interfascicular trigeminal nucleus) | Cbln1, NeuroD2, Vglut1, Zic1 |
| TRN (tegmental reticular nucleus) | Camk4, NeuroD2, Vglut1, Zic1, Zic2 | |
| PG (pontine gray) | Camk4, NeuroD2, Vglut1, Zic1, Zic2 | |
| KF (koelliker-fuse subnucleus) | Calb1 |