Table 5.
Meta-analyses for effects of the ERAS programs on postoperative morbidity and mortality
| Outcomes | Number of studies | Sample size
|
Heterogeneity(I2, p) | Model | RR with 95% CI | p-Value | Publication bias
|
Conclusion | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | ERAS | Control | Begg (p) | Egger (p) | |||||||
| Overall analysis | |||||||||||
| Overall morbidity | 7 | 486 | 243 | 243 | I2=1.9%, p=0.42 | Fixed | 0.64 (0.51–0.80) | <0.001 | 0.59 | 0.31 | Significant |
| In-hospital mortality | 4 | 329 | 164 | 165 | I2=0.0%, p=0.89 | Fixed | 0.70 (0.19–2.53) | 0.58 | 0.17 | 0.13 | Not significant |
| Subgroup analyses | |||||||||||
| Pulmonary complications | 7 | 486 | 243 | 243 | I2=0.0%, p=0.59 | Fixed | 0.43 (0.31–0.60) | <0.001 | 1.0 | 0.46 | Significant |
| Surgical complications | 5 | 377 | 188 | 189 | I2=0.0%, p=0.74 | Fixed | 0.46 (0.25–0.83) | 0.010 | 0.81 | 0.23 | Significant |
| Cardiovascular complications | 4 | 304 | 151 | 153 | I2=0.0%, p=0.96 | Fixed | 1.46 (0.77–2.77) | 0.25 | 1.0 | 0.61 | Not significant |
Abbreviations: ERAS, enhanced recovery after surgery; RR, relative risk.