Table 3.
Comparison of CR, nCR, PR, MR, SD, PD, NR, ORR, and DCR between the experimental and control groups
| Parameter | Number of patients (n)
|
Analysis method | Heterogeneity
|
OR | 95% CI | P-value | ||
|---|---|---|---|---|---|---|---|---|
| Experimental group | Control group | I2 (%) | P-value | |||||
| CR | 252 | 250 | Fixed | 0 | 0.98 | 2.71 | 1.60–4.58 | 0.0002 |
| nCR | 105 | 102 | Fixed | 0 | 0.88 | 1.35 | 0.58–3.11 | 0.48 |
| PR | 252 | 250 | Fixed | 0 | 1.00 | 1.49 | 1.01–2.20 | 0.04 |
| MR | 162 | 160 | Fixed | 0 | 0.79 | 0.91 | 0.52–1.57 | 0.73 |
| SD | 100 | 102 | Fixed | 0 | 0.58 | 0.66 | 0.35–1.25 | 0.21 |
| PD | 191 | 188 | Fixed | 0 | 0.89 | 0.34 | 0.20–0.58 | <0.0001 |
| NR | 47 | 46 | Fixed | 15 | 0.28 | 0.24 | 0.07–0.80 | 0.02 |
| ORR | 252 | 250 | Fixed | 0 | 0.99 | 2.77 | 1.88–4.10 | <0.00001 |
| DCR | 191 | 188 | Fixed | 0 | 0.89 | 2.90 | 1.72–4.90 | <0.0001 |
Abbreviations: CI, confidence interval; CR, complete response; DCR, disease control rate; MR, minuteness response; nCR, near CR; NR, nonresponse; OR, odds ratio; ORR, overall response rate; PD, progressive disease; PR, partial response; SD, stable disease.