Table 4.
Comparison of lymphocyte subsets before and after DC–CIK therapy
| Parameter | DC–CIK
|
Analysis method | Heterogeneity
|
OR | 95% CI | P-value | ||
|---|---|---|---|---|---|---|---|---|
| After treatment (n) | Before treatment (n) | I2 (%) | P-value | |||||
| CD4+ | 86 | 86 | Fixed | 43 | 0.17 | 3.14 | 1.65 to 4.64 | <0.0001 |
| CD8+ | 86 | 86 | Fixed | 55 | 0.11 | −9.26 | −11.58 to −6.95 | <0.00001 |
| CD4+/CD8+ | 86 | 86 | Fixed | 72 | 0.03 | 0.38 | 0.18 to 0.59 | 0.0002 |
| CD4+CD25+ | 88 | 88 | Fixed | 80 | 0.002 | −2.97 | −4.44 to −1.50 | <0.0001 |
Abbreviations: CI, confidence interval; DC–CIK, dendritic cells and cytokine-induced killer cells; OR, odds ratio.