Table 7.
Parameter | Number of patients (n)
|
Number of patients (n)
|
Analysis method | Heterogeneity
|
OR | 95% CI | P-value | |
---|---|---|---|---|---|---|---|---|
Exp group | Con group | I2 (%) | P-value | |||||
ORR | ||||||||
With low quality | 252 | 250 | Fixed | 0 | 0.99 | 2.77 | 1.88–4.10 | <0.00001 |
Without low quality | 213 | 216 | Fixed | 0 | 0.97 | 2.75 | 1.79–4.21 | <0.00001 |
With CIK therapy | 252 | 250 | Fixed | 0 | 0.99 | 2.77 | 1.88–4.10 | <0.00001 |
Without CIK therapy | 208 | 204 | Fixed | 0 | 1.00 | 2.67 | 1.75–4.08 | <0.00001 |
DCR | ||||||||
With low quality | 191 | 188 | Fixed | 0 | 0.89 | 2.90 | 1.72–4.90 | <0.0001 |
Without low quality | 169 | 170 | Fixed | 0 | 0.92 | 2.70 | 1.57–4.64 | 0.0003 |
Notes: Con, control group (chemotherapy alone group); Exp, experimental group (chemotherapy plus DC–CIK immunotherapy).
Abbreviations: CI, confidence interval; CIK, cytokine-induced killer cells; DC–CIK, dendritic cells and CIK; DCR, disease control rate; OR, odds ratio; ORR, overall response rate.