Table 1. Characteristics of the total study cohort also split by ISAR score and CGA results.
| Total (n = 381) |
ISAR- (n = 54; 15.2%) |
ISAR+/CGA normal (n = 52; 14.7%) |
ISAR+/CGA abnormal (n = 248; 70.1%) |
p-value ISAR+/CGA normal vs ISAR- | p-value ISAR+/CGA abnormal vs ISAR- | p-value ISAR+/CGA abnormal vs ISAR+/CGA normal | |
|---|---|---|---|---|---|---|---|
| Age (years) | 82.5±5.5 | 79.3±3.8 | 80.8±4.7 | 83.4±5.5 | 0.185 | <0.001 | 0.003 |
| Sex (male) | 95(24.9) | 20(37.0) | 12(23.1) | 57(23.0) | 0.138 | 0.036 | 0.999 |
| Anemia | 18(4.7) | 0 | 0 | 18(7.3) | 0.999 | 0.051 | 0.051 |
| Chronic kidney disease | 55(14.4) | 6(11.1) | 5(9.6) | 43(17.3) | 0.999 | 0.315 | 0.213 |
| Heart failure | 45(11.8) | 1(1.9) | 4(7.7) | 39(15.7) | 0.205 | 0.006 | 0.190 |
| Coronary heart disease | 64(16.8) | 3(5.6) | 10(19.2) | 48(19.4) | 0.015 | 0.007 | 0.999 |
| Atrial fibrillation | 70(18.1) | 4(7.4) | 8(15.4) | 56(22.6) | 0.236 | 0.013 | 0.272 |
| Other cardiac arrhythmias | 32(8.4) | 2(3.7) | 4(7.7) | 26(10.5) | 0.437 | 0.190 | 0.623 |
| Valve insufficiency | 34(8.9) | 3(5.6) | 3(5.8) | 26(10.5) | 0.999 | 0.322 | 0.325 |
| Chronic obstructive pulmonary disease | 24(6.3) | 0 | 4(7.7) | 17(6.9) | 0.057 | 0.092 | 0.999 |
| Peripheral artery disease | 11(2.9) | 2(3.7) | 1(1.9) | 6(2.4) | 0.999 | 0.634 | 0.999 |
| Arterial hypertension | 260(68.2) | 40(74.1) | 34(65.4) | 169(68.1) | 0.402 | 0.514 | 0.745 |
| Diabetes | 79(20.7) | 6(11.1) | 9(17.3) | 60(24.2) | 0.416 | 0.044 | 0.365 |
| Hyperlipoproteinemia | 23(6.0) | 3(5.6) | 2(3.8) | 17(6.9) | 0.999 | 0.782 | 0.545 |
| Nicotine abuse | 5(1.3) | 0 | 1(1.9) | 4(1.6) | 0.495 | 0.603 | 0.999 |
| Obesity | 12(3.1) | 0 | 2(3.8) | 8(3.2) | 0.243 | 0.359 | 0.686 |
| History of myocardial infarction | 25(6.6) | 1(1.9) | 6(11.5) | 17(6.9) | 0.013 | 0.050 | 0.254 |
| History of pulmonary embolism | 10(2.6) | 0 | 3(5.8) | 7(2.8) | 0.118 | 0.361 | 0.386 |
| History of stroke | 27(7.1) | 2(3.7) | 3(5.8) | 21(8.5) | 0.678 | 0.279 | 0.778 |
| History of thrombosis | 14(3.7) | 2(3.7) | 3(5.8) | 9(3.6) | 0.678 | 0.999 | 0.443 |
| Hyperthyroidism | 5(1.3) | 2(3.7) | 1(1.9) | 2(0.8) | 0.999 | 0.144 | 0.436 |
| Hypothyroidism | 45(11.8) | 5(9.3) | 5(9.6) | 32(12.9) | 0.999 | 0.510 | 0.646 |
| Dementia | 69(18.1) | 1(1.9) | 5(9.6) | 53(21.4) | 0.113 | 0.001 | 0.054 |
| Alcohol abuse | 12(2.1) | 0 | 0 | 10(4.0) | 0.999 | 0.219 | 0.220 |
| Depression | 23(6.0) | 3(5.6) | 2(3.8) | 12(4.8) | 0.999 | 0.999 | 0.999 |
| Anxiety disorder | 5(1.3) | 0 | 1(1.9) | 4(1.6) | 0.495 | 0.603 | 0.999 |
| Parkinson’s disease | 14(3.7) | 3(5.6) | 1(1.9) | 9(3.6) | 0.618 | 0.449 | 0.999 |
| Polyneuropathy | 13(3.4) | 3(5.6) | 2(3.8) | 6(2.4) | 0.999 | 0.369 | 0.631 |
| Cancer | 53(13.9) | 8(14.8) | 4(7.7) | 38(15.3) | 0.359 | 0.999 | 0.189 |
| Cataract | 15(3.9) | 1(1.9) | 2(3.8) | 12(4.8) | 0.618 | 0.477 | 0.999 |
| Presbyacusia | 8(2.1) | 2(3.7) | 0 | 6(2.4) | 0.495 | 0.634 | 0.595 |
| Anal incontinence | 2(0.5) | 0 | 0 | 1(0.4) | 0.999 | 0.999 | 0.999 |
| Urinary incontinence | 11(2.9) | 1(1.9) | 0 | 7(2.8) | 0.999 | 0.999 | 0.609 |
| Decubitus | 7(1.8) | 0 | 1(1.9) | 6(2.4) | 0.495 | 0.379 | 0.999 |
CGA, comprehensive geriatric assessment; ISAR, Identification of Seniors at Risk. ISAR+, positive ISAR screening (score ≥2); ISAR-, negative ISAR screening (score <2). In 327 ISAR+ patients, 300 CGAs were performed (27 missing due to transfer, discharge, foreign-language or incompliance of patients). For definition of abnormal CGA see section ‘Comprehensive geriatric assessment’ in ‘Materials and Methods‘.