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. 2017 Nov 3;7(11):e017308. doi: 10.1136/bmjopen-2017-017308

Table 3.

Baseline median and trend in monthly PDC for OH and AH medicines, and changes in level and trend by stage of the ‘FP’ programme, Brazil, 2008–2012

Baseline AFP-II (Apr 2009) SNP (Feb 2011)
Level (PDC) Trend PDC (Mar 2009) Level AFP-II (change at the intervention) Trend AFP-II % Relative change
(AFP-II) (Apr 2010)
PDC (Jan 2011) Level SNP
(change at the intervention)
Trend SNP % Relative change
(SNP)
(Feb 2012)
OH 59.67 0.30 64.22 −8.1 (−12.85;−3.36) 0.28 (−0.12;0.67) −9.0 67.21 4.88 (0.37;9.39) −0.43 (−0.79;−0.07) 2.5
 Glibenclamide 5 mg 61.40 0.56 69.75 −15.23 (−19.65;−10.81) −0.07 (−0.43;0.3) −20.4 65.73 6.23 (2.03;10.42) −0.35 (−0.68;−0.01) 5.3
 Metformin 850 mg 59.02 0.38 64.74 −10.41 (−15.3;−5.52) 0.21 (−0.2;0.62) −12.8 66.08 3.84 (−0.81;8.49) −0.37 (−0.74;−0.01) 1.7
 *Metformin 500 mg 56.24 0.05 57.04 −1.75 (−7.23;3.73) 2.87 (0.07;5.67) 6.7 64.41 8.56 (2.9;14.22) −0.15 (−0.77;0.46) 11.2
 Metformin slow release 61.09 0.15 63.29 0.61 (−10.35;11.57) 0.16 (−0.75;1.06) 2.6 69.67 11.09 (0.61;21.56) −0.43 (−1.25;0.4) 11.0
Oral AH 63.98 0.45 70.74 −10.63 (−14.7;−6.55) 0.22 (−0.12;0.55) −11.9 73.48 4.87 (1;8.73) −0.57 (−0.88;−0.27) 1.0
 *Atenolol 25 mg 64.88 0.02 65.15 −0.70 (−5.53;4.13) 3.4 (1.03;5.78) 9.1 74.27 10.63 (6.6;14.67) −0.14 (−0.49;0.21) 12.6
 Propranolol 40 mg 61.34 1.07 77.40 −26.21 (−32.49;−19.93) −0.73 (−1.25;−0.21) −34.3 63.00 11.63 (5.66;17.6) −0.23 (−0.71;0.24) 14.8
 Hydrochlorothiazide 25 mg 56.88 0.82 69.22 −18.17 (−22.91;−13.43) −0.12 (−0.51;0.28) −23.8 67.25 10.1 (5.6;14.6) −0.53 (−0.89;−0.17) 8.4
 Captopril 25 mg 63.81 0.99 78.66 −23.07 (−28.85;−17.29) −0.52 (−1;−0.04) −29.2 69.11 5.86 (0.37;11.35) −0.38 (−0.82;0.06) 4.2
 *Enalapril 5 mg 70.16 0.02 70.39 −2.91 (−7.74;1.93) 2.56 (0.18;4.95) 3.0 74.93 7.79 (3.75;11.83) −0.02 (−0.37;0.34) 10.0

Significant values p<0.05 are highlighted in bold.

*It used the Log of the AFP-II trend.

AFP-II, Aqui tem Farmácia Popular II; AH, antihypertensive; FP, Farmácia Popular; NA, no applicable; OH, oral hypoglycaemic; PDC, proportion of days covered; SNP, Saúde Não Tem Preço.