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. 2017 Nov 3;7(11):e017504. doi: 10.1136/bmjopen-2017-017504

Table 1.

Comparison of demographic and clinical data between DLB and AD cohorts

Characteristic DLB (n=251) AD (n=222) χ2 or F test statistic p Value
Gender
 Female 129 (51.4%) 139 (62.6%) χ2 1 = 6.04 0.01
 Male 122 83
Age at first presentation with cognitive impairment (years) 78.8 (SD 7.7) (n=251) 79.5 (SD 8.8) (n=200) F1,449 =2.51 0.11
Age at diagnosis (years) 79.3 (SD 7.6) 80.2 (SD 8.8) F1,471 =1.32 0.25
MMSE score at diagnosis 20.1 (SD 5.5) (n=183) 20.6 (SD 4.9) (n=172) F1,353 <1 0.41
Charlson comorbidity index at diagnosis
 Low comorbidity (score ≤2) 183 (72.9%) 158 (71.2%) χ2 1 = 0.18 0.67
 High comorbidity (score >2) 68 64
Medications prescribed
 Antipsychotic (neuroleptic) drugs 103 (41.0%) 32 (14.4%) χ2 1 = 39.6 <0.0001
 Parkinson’s disease drugs 93 (37.1%) 0 (0%) χ2 1 = 102.39 <0.0001
 Antidementia drugs 152 (60.6%) 139 (62.6%) χ1 = 0.21 0.65

AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; MMSE, Mini-Mental State Examination.