Table 3.
Prevalence of prescribed medications used by patients with lower extremity amputations in 2010–2011 in Denmark
| Major amputations | Minor amputations | ||||
| Total, n (%) | Above knee, n (%) | Below knee, n (%) | Total, n (%) | p Value* | |
| n=1782 | n=1024 | n=758 | n=1101 | ||
| Opioids | 1484 (83) | 876 (86) | 608 (80) | 684 (62) | <0.0001 |
| Antithrombotic drugs | 1262 (71) | 738 (72) | 524 (69) | 711 (65) | 0.0005 |
| Acetaminophen | 1333 (75) | 802 (78) | 531 (70) | 621 (56) | <0.0001 |
| Antihypertensives | 1000 (56) | 577 (56) | 423 (56) | 715 (65) | <0.0001 |
| Cholesterol-lowering drugs | 886 (50) | 481 (47) | 405 (53) | 627 (57) | 0.0002 |
| Neuropathic pain relievers | 919 (52) | 517 (50) | 402 (53) | 330 (30) | <0.0001 |
| Antidepressants | 864 (48) | 501 (49) | 363 (48) | 365 (33) | <0.0001 |
| Antidiabetic therapy | 588 (33) | 268 (26) | 320 (42) | 638 (58) | <0.0001 |
| Beta blockers | 760 (43) | 440 (43) | 320 (42) | 439 (40) | 0.14 |
| NSAID | 451 (25) | 264 (26) | 187 (25) | 312 (28) | 0.07 |
| Drugs for airway disease | 337 (19) | 199 (19) | 138 (18) | 146 (14) | <0.0001 |
| Alcohol addiction | 341 (19) | 198 (20) | 143 (19) | 122 (11) | <0.0001 |
| Smoking cessation | 259 (15) | 155 (15) | 104 (14) | 132 (12) | 0.053 |
| Cortisol | 246 (14) | 156 (15) | 90 (12) | 120 (11) | 0.023 |
*p<0.05, major vs minor amputation.
NSAID, non-steroidal anti-inflammatory drug.