Table 5.

Haplotype association analysis for rs2272127, rs2293225 and rs7559479 in the IL18RAP gene with the body mass index (BMI) and obesity risk adjusted for age and sex

No	Haplotype	Frequency		Freq.	OR (95% CI)	P value	BMI
		Non-obese	Obese				Difference (95% CI)	P value
1	CCA	0.344	0.308	0.337	1.00	–	0.00	–
2	CCG	0.220	0.277	0.232	1.44 (1.15 to 1.80)	0.0015	0.48 (0.12 to 0.85)	0.0088
3	GCA	0.225	0.232	0.226	1.13 (0.90 to 1.43)	0.30	0.08 (−0.29 to 0.44)	0.68
4	CTA	0.206	0.175	0.199	0.95 (0.74 to 1.21)	0.68	−0.2 (−0.57 to 0.17)	0.29

SNPs used in the haplotype construction: rs2272127, rs2293225 and rs7559479.

Bold indicates significance.

Freq, frequency.